Skip to main content
. Author manuscript; available in PMC: 2012 Oct 1.
Published in final edited form as: Int J Antimicrob Agents. 2012 Jul 20;40(4):354–360. doi: 10.1016/j.ijantimicag.2012.05.023

Figure 2.

Figure 2

Figure 2

HIV-1 is inhibited by salicylidene acylhydrazides using TZMbl indicator cells (a) or PHA-stimulated primary PBMCs (b) as targets for virus growth. A clinical clade B R5 strain (HIV-1US657) was used as cell-free virus with both target cells. Similar virus inhibition was observed with two additional clade B R5 strains, HIV-1US005 (c) and HIV-1US712 (d). The compounds also inhibit HIV-1 after exposure of TZMbl target cells to cell-associated virus (e), where CEM.NKr-CCR5 cells, infected for three days with HIV- 1US657 were incubated with TZMbl cells in the presence of compounds INP0149 or INP0341. Shown are means ± standard errors of assays repeated two or three times. Horizontal dotted line indicates 50% virus inhibition.