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. Author manuscript; available in PMC: 2012 Oct 1.
Published in final edited form as: Int J Antimicrob Agents. 2012 Jul 20;40(4):354–360. doi: 10.1016/j.ijantimicag.2012.05.023

Table 1.

Anti-HIV-1 activity of salicylidene acylhydrazides1.

Compound IC50 (μM) Cyt25 (μM)
INP0149 0.9 12.5
INP0161 1.3 >25
INP0341 2.3 >25
INP0400 7.3 >25
1

Compounds were assayed against HIV-1US657, a primary R5 isolate, using TZMbl target cells. Percentage inhibition was calculated based on a DMSO control (no compound). IC50 refers to concentration of compound resulting in ≥50% virus inhibition; Cyt25 refers to concentration resulting in ≥25% cytotoxicity of TZMbl cells by propidium iodine staining.