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. Author manuscript; available in PMC: 2013 Sep 1.
Published in final edited form as: Birth Defects Res A Clin Mol Teratol. 2012 Jul 18;94(9):683–692. doi: 10.1002/bdra.23040

Table 2.

NTD candidate genes with differential temporal and spatial expression. ROS12, rostral C12; ROS13, rostral C13; CAU12, caudal C13; CAU13, caudal C13.

Gene Region Temporal Expr.Change p Spatial Expr. Change p
CBS Rostral Up ROS13 vs ROS12 0.023 Down CAU13 vs ROS13 0.0054
CD99 Caudal Up CAU13 vs CAU12 0.0001 Up CAU13 vs ROS13 0.0039
FKBP8 Rostral Down CAU13 vs ROS13 0.323
GTF2IRD1 Caudal Up CAU13 vs CAU12 0.0314 Up CAU13 vs ROS13 0.0321
IGF2 Caudal Up CAU13 vs CAU12 0.002 Up CAU13 vs ROS13 0.0406
ITGB1 Caudal Up CAU13 vs CAU12 0.001 Up CAU13 vs ROS13 0.0107
MSX1 Caudal Up CAU13 vs CAU12 0.0069 Up CAU13 vs ROS13 0.0475
PFN1 Rostral Up ROS13 vs ROS12 0.0013 Down CAU13 vs ROS13 0.0111
POR Caudal Up CAU13 vs ROS13 0.0042
SALL1 Caudal Up CAU13 vs ROS13 0.0069
SLC2A1 Caudal Up CAU13 vs CAU12 0 Up CAU13 vs ROS13 0.0002
TPT1* Caudal Up CAU13 vs ROS13 0.0049
*

Two tags were significantly different between CAU13 and ROS13 for TPT1; the most significant p value is given.