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. Author manuscript; available in PMC: 2013 Dec 1.
Published in final edited form as: Neuropharmacology. 2012 Aug 5;63(7):1238–1247. doi: 10.1016/j.neuropharm.2012.07.047

Figure 1. 5-HT1A receptors are present in astrocytes in the SVZ and SGZ of adult C57BL/6J mice.

Figure 1

5-HT1A receptor (A) and GFAP (B) are co-localized (C) in the SVZ. Confocal microscopy shows that 5-HT1A receptor (D) and GFAP (E) are almost exclusively co-localized (F), as indicated in the z-stack, except for a few putative axon terminals, presumably presynaptic receptors of serotonergic projections (arrows). In the dentate gyrus, 5-HT1A receptor (G) and GFAP (H) also shows co-localization (I), including in the SGZ. Scale bar 100 µm (A–C, H–I), 10 µM (D–F). CC = corpus callosum, GCL = granule cell layer, H = hilus, LV = lateral ventricle, STR = striatum.