Table 1. z-Scores of high-rank candidate genes.
Ethanol |
UV |
||||
---|---|---|---|---|---|
Gene | Description | Amplicon 1 | Amplicon 2 | Amplicon 1 | Amplicon 2 |
Control | |||||
AmpR | Bacterial gene | 0 | 0 | ||
Known benchmarks | |||||
Dronc | Apical caspase | 36.3 | 25.0 | ||
Ethanol-specific suppressors | |||||
CG1600 | ADH_N domain | 12.3 | 13.2 | −2.0 | −1.3 |
CG6899 (Ptp4E) | Protein tyrosine phosphatase | 9.3 | 7.9 | −0.6 | −0.4 |
CG9946 | eIF-2α | 3.7 | 3.4 | −1.7 | −0.8 |
CG14478 | DNA methylase domain | 4.1 | 3.8 | 0.0 | −1.3 |
CG8108 | Zinc finger, C2H2-like | 7.9 | 5.1 | −1.0 | −1.3 |
CG1793 (MED26) | RNA polymerase II transcription mediator | 10.3 | 8.5 | −2.3 | −1.4 |
Ethanol-specific enhancer | |||||
CG9375 (Ras85D) | Ras GTPase | −3.7 | −4.6 | 1.5 | 0.7 |
Common death suppressors | |||||
CG9204 (Ate1) | Arginine-tRNA-protein transferase | 17.1 | 10.3 | 11.0 | 13.8 |
CG32579 | Membrane transport protein XK-like | 4.9 | 6.4 | 7.3 | 7.5 |
CG10811 | eIF4G | 7.1 | 7.1 | 2.1 | 4.2 |
Cell survival was measured using CellTiter-Glo, and z-scores were calculated relative to control mean and standard deviation. Data shown are the average from at least two independent experiments