Table 1.
Relative binding affinity of GD3 to human and mouse CD1d molecules
| Ligand (Competitor) | IC50 in hCD1d (nM) | IC50 in mCD1d (nM) |
|---|---|---|
| 18:1 PE lipid | 882 ± 125 | 843 ± 181 |
| GD3(CHCl3+CH3OH) | 24.6 ± 3.2 | 10.5 ± 1.5 |
| α-GalCer | 84.0 ± 10.0 | 95.1 ± 18.3 |
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