Immunohistochemical staining of MAD2 in locally advanced cervical cancer. (A) Negative control; (B) Group NAC+R, score 1; (C) Group NAC+OP+R, score 12; (A–C, H&E, x400). MAD2 was expressed in the nuclei of the tumor cells. MAD2, mitotic arrest deficiency 2; NAC+R, neoadjuvant chemotherapy + radiotherapy; NAC+OP+R, neoadjuvant chemotherapy + surgery + radiotherapy; H&E, hematoxylin and eosin.