Table V.
Parameter | No. | Median survival (months; 95% CI) | P-value | Hazard ratio (95% CI) |
---|---|---|---|---|
Multi-drug vs. single-drug regimen | ||||
Multi-drug | 58 | 7.6 (6.0–10.0) | ||
Single-drug | 35 | 7.6 (4.2–15.6) | 0.743 | 0.92 (0.57–1.49) |
Gemcitabine, fluorouracil and combined regimen | ||||
Gemcitabine | 50 | 7.6 (6.0–14.2) | ||
Fluorouracil | 25 | 5.0 (3.7–10.0) | ||
Combined | 18 | 9.3 (7.1–11.0) | 0.364 | 1.09 (0.90–1.32) |
Gemcitabine | ||||
Yes | 68 | 9.0 (7.1–11.0) | ||
No | 25 | 5.0 (3.7–10.0) | 0.956 | 0.99 (0.58–1.68) |
Fluorouracil | ||||
Yes | 43 | 7.4 (4.5–10.0) | ||
No | 50 | 7.6 (6.0–14.2) | 0.504 | 1.17 (0.74–1.84) |
Platinum (1) | ||||
With | 48 | 10.0 (7.6–14.0) | ||
Without | 47 | 5.0 (3.2–7.1) | 0.011 | 0.56 (0.35–0.88) |
Platinum (2) | ||||
Cisplatin | 8 | 7.9 (5.1–17.0) | ||
Carboplatin | 15 | 9.6 (6.0–17.3) | ||
Oxaliplatin | 23 | 12.4 (10.0–19.0) | 0.093 | 0.70 (0.46–1.06) |