Table II.

Laboratory analysis of the urine samples and dimercaptosuccinic acid uptake in the study groups.

	Control	Ischemia/reperfusion + leptin	Ischemia/reperfusion + apelin	Ischemia/reperfusion	P-value
24-hour urine protein (mg/dl)	114.00±11.86	117.88±9.60	117.63±9.86	117.63±10.61	>0.05
24-hour urine sodium (mmol/l)	109.63±18.49	110.50±20.78	110.75±19.35	124.12±44.46	>0.05
24-hour urine potassium (mmol/l)	140.25±14.12	140.13±13.80	140.88±15.12	141.38±13.84	>0.05
24-hour urine chloride (mmol/l)	127.38±15.76	129.25±20.06	129.50±19.15	130.50±15.37	>0.05
24-hour urine urea (mg/dl)	1,013.75±6.94	1,012.50±6.55	1,010.63±6.23	1,011.88±7.04	>0.05
Urine density	7,568.75±481.77	7,405.00±636.04	7,405.00±634.58	7,400.00±681.60	>0.05
Glomerular filtration rate (ml/min)	2.43±1.26b	0.68±0.35a	1.66±0.49	1.71±0.34	0.001
99mTc dimercaptosuccinic acid uptake (%)	33.30±11.06c	18.37±8.50	17.48±5.91a	18.76±6.98	0.03

For each group, n=8. Values are presented as mean ± SD.

^aDifferent from the control group,

^bDifferent from the ischemia/reperfusion group,

^cDifferent from the ischemia/reperfusion + leptin group. P-value in bold print indicates a significant difference.