Table IV.

Multivariate analysis of the clinicopathological factors and the expression of MCT4 in patients with colorectal cancer.

Factor	p-value	Hazard ratio	95% CI
TNM stage (I, II, III vs. IV)	<0.0001	0.108	0.040–0.290
N (− vs. +)	0.0120	0.124	0.024–0.632
MCT4 expression (negative vs. positive)	0.0201	3.163	1.198–8.356
Histological type (diff. vs. undiff.)	0.1302	0.438	0.150–1.276
Venous invasion (− vs. +)	0.1820	0.544	0.223–1.330
T (T1, T2, T3, T4a vs. T4b)	0.7348	1.160	0.491–2.744
Lymphatic invasion (weak vs. strong)	0.8877	0.934	0.361–2.417

The weak group of lymphatic invasion indicated score 0 and 1, and the strong group indicated score 2 and 3 by the Japan Classification of Colorectal Cancer.