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Expression of HIF 1α in UTUC with relation to angiogenesis and apoptosis related biomarkers
| Molecular marker | N 104 | HIF 1α normal (N = 60) | HIF 1α altered (N = 50) | p < |
|---|---|---|---|---|
| Expression N (%) | ||||
| Bcl-2 | 0.01 | |||
| 1 | 88 (84.6) | 54 (93.1) | 34 (73.9) | |
| 2 | 16 (15.4) | 4 (6.9) | 12 (26.1) | |
| Caspase-3 index* | ||||
| X± SD | 2.55±7.42 | 1.64±7.61 | 3.72±7.09 | 0.005 |
| MVD CD34* | ||||
| X± SD | 22.46±10.68 | 21.18±12.12 | 23.99±8.53 | 0.01 |
χ2 test was performed.
Mann Whitney U test was performed
