Table 3.
Genotype and Allele Frequencies of the CYP27B1-1260 and VDR Taq I Polymorphisms in Hepatitis B Virus Patients with Different Clinical Diagnosis
| Polymorphism | Chronic hepatitis (n=94) | Cirrhosis (n=90) | HCC (n=90) | p |
|---|---|---|---|---|
| CYP27B1-1260 | ||||
| Genotype | ||||
| AA | 31 (33.0%) | 38 (42.2%) | 36 (40.0%) | Reference |
| AC | 47 (50.0%) | 41 (45.6%) | 40 (44.4%) | 0.509 |
| CC | 16 (17.0%) | 11 (12.2%) | 14 (12.2%) | 0.450 |
| Allele | ||||
| A | 109 (58.0%) | 117 (65.0%) | 112 (62.2%) | Reference |
| C | 79 (42.0%) | 63 (35.0%) | 68 (37.8%) | 0.163 |
| VDR Taq I | ||||
| Genotype | ||||
| TT | 82 (87.2%) | 81 (90.0%) | 76 (84.4%) | Reference |
| Tt | 12 (12.8%) | 9 (10.0%) | 14 (15.6%) | 0.536 |
| tt | 0 | 0 | 0 | — |
| Allele | ||||
| T | 176 (93.6%) | 171 (95.0%) | 166 (92.2%) | Reference |
| t | 12 (6.4%) | 9 (5.0%) | 14 (7.8%) | 0.559 |
Data are presented as n (%).
HCC, hepatocellular carcinoma.