Figure 1.
(a) Representative autoradiograph showing LOH in non-small cell lung cancer. Above each autoradiograph, microsatellite marker; under each autoradiograph, patient's identification number; arrowheads, the allele losses; N, normal DNA;T, Tumor DNA. For each sample, the left panel, lung tumor without LOH; the right panel, lung tumor with LOH. (b) Representative example for Kras2 gene codon 12 mutation. On the left, lung tumor without Kras2 mutation; on the right, lung tumor with Kras2 gene 12th codon mutation (GGT→TGT transition)