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Correlation between LOH on chromosome 12p and Kras2 activation in nonsmall cell lung cancer
| Tumor type | Patient number | Kras2 mutation | Frequency of LOH on chromosome 12p | Tumors with Kras2 mutations and LOH |
|---|---|---|---|---|
| Adenocarcinoma | 22 | 9/22 (40.9%) | 10/22 (45.5%) | 9/10 (90.0%) |
| Large cell carcinoma | 8 | 3/8 (37.5%) | 4/8 (50.0%) | 3/4 (75.0%) |
