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. 2012 Jul 24;287(37):30975–30983. doi: 10.1074/jbc.M112.374306

FIGURE 1.

FIGURE 1.

Conversion of 5α-AD to ADD by Δ1-KSTD (EC 1.3.99.4) and Δ4-KSTD (EC 1.3.99.5). The two double bonds introduced by the enzymes are indicated. The intermediate products 1-(5α)-AD and 4-AD are 1-(5α)-androstene-3,17-dione and 4-androstene-3,17-dione, respectively.