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AT1R dependence of the effect of Ang II on arterial tone. Effect of the specific AT1R inhibitor candesartan (Cand, 10 μm) on the Ang II-induced (0.1–100 nm) vasoconstriction in rat gracilis arterioles (n = 4–5). Mean ± S.E. values are shown. Asterisks indicate significant effects of the inhibitor on Ang II-induced vasoconstriction (p < 0.05).
