TABLE 1.
Geometric values of isolated arteries
Control (CD) and passive (PD, relaxed) diameter (μm) and spontaneous tone values of rat and mouse gracilis arterioles and mouse saphenous arteries (mouse a. saphena) are shown. Mean ± S.E. values and number of segments (n) are indicated for each vessel type. Vascular tone was calculated as percent contraction related to passive diameter. Values for rat saphenous arteries were separated as of wild type (control) and CB1R knockout mice.
| Prepared segments | CD | PD | Tone | n |
|---|---|---|---|---|
| μm | μm | % | ||
| Rat gracilis arteriole | 123.7 ± 5.4 | 152.9 ± 6.6 | 18.5 ± 1.7 | 38 |
| Mouse gracilis arteriole | 119.4 ± 7.0 | 135.8 ± 5.4 | 12.3 ± 1.8 | 5 |
| Mouse a. saphena (control mice) | 185.4 ± 15.0 | 216.7 ± 17.0 | 13.7 ± 3.3 | 10 |
| Mouse a. saphena (CB1 ko mice) | 179.4 ± 17.2 | 210.1 ± 21.4 | 13.9 ± 2.2 | 5 |