Figure 6.

Activation of ERK and AKT (also known as Protein Kinase B [PKB]) by T₃. Following an acute exposure to T₃, ERK phosphorylation is greater with increasing T₃ concentrations (A). AKT phosphorylation, however, increases equally with all three doses of T₃. Data are mean ± standard error of mean, each bar n = 7, *P < .05, and **P < .01 versus serum free control. ERK indicates extracellular signal-related kinase; T₃, 3,3′,5-tri-iodo-l-thyronine.