GEM and Ara-C sensitivity in MTA-resistant cells. Cytotoxicity of GEM and Ara-C in PC6, PC6/MTA-0.4 and PC6/MTA-1.6 cells. GEM, gemcitabine; Ara-C, cytosine arabinoside; MTA, pemetrexed; IC50, concentration for 50% cell survival; CI, confidence interval; RR, resistance rate.