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Relation of Risk Factors to Neuropathologic Indices
| Risk Factor | Association with Neuropathology | Reduced Association of Pathology with Cognition |
|---|---|---|
| APOE ε4 | AD | |
| APOE ε2 | AD | |
| CR1 | AD | |
| CEPT | AD | |
| PICALM | ||
| Neuroticism | ||
| Anxiety | ||
| Vulnerability to stress | ||
| Social networks | AD | |
| Purpose in life | AD | |
| Processing resources | AD | |
| Cognitive activity | ||
| Loneliness | ||
| Oder identification | AD, Lewy bodies | |
| Grip strength | AD | |
| Physical frailty | AD | |
| Parkinsonian signs | AD, Infarcts, Lewy bodies |
