Figure 2.

Sevoflurane MAC during intrathecal administration of CO₂-acidified aCSF (MAC-aCSF) and during administration of acidified aCSF containing 0.4 mg/mL dizocilpine (MAC-dizocilpine), either without (control) or with 4 mg/mL strychnine. The strychnine MAC values were both significantly greater than their corresponding control sevoflurane MAC values (* P < 0.05) The difference in sevoflurane MAC before and after dizocilpine administration is shown in the far right bars for both control (C) and strychnine (S) rats.