Table 1.
A breakdown of the 6 comparisons for BT474 and SKBR3
| Comparison | Cell Line | Groups | Treatment | Time Point | Sample Number |
|---|---|---|---|---|---|
| 1 |
BT474 |
Group 1 |
1 μM lapatinib |
6 hr & 12 hr |
8 |
| Group 2 |
0.1 μM lapatinib |
2 hr & 6 hr & 12 hr & 24 hr |
16 |
||
| 1 μM lapatinib |
2 hr |
4 |
|||
| 0.1% DMSO |
0 hr & 2 hr & 6 hr & 12 hr & 24 hr |
20 |
|||
|
Total |
|
|
48 |
||
| 2 |
BT474 |
Group 1 |
1 μM lapatinib |
6 hr & 12 hr |
8 |
| Group 2 |
0.1 μM lapatinib |
6 hr & 12 hr |
8 |
||
|
Total |
|
|
16 |
||
| 3 |
SKBR3 |
Group 1 |
1 μM lapatinib |
6 hr & 12 hr |
8 |
| 0.1 μM lapatinib |
6 hr & 12 hr |
8 |
|||
| Group 2 |
0.1 μM lapatinib |
2 hr & 24 hr |
8 |
||
| 1 μM lapatinib |
2 hr |
4 |
|||
| 0.1% DMSO |
0 hr & 2 hr & 6 hr & 12 hr & 24 hr |
20 |
|||
|
Total |
|
|
48 |
||
| 4 |
SKBR3 |
Group 1 |
1 μM lapatinib |
6 hr & 12 hr |
8 |
| 0.1 μM lapatinib |
6 hr & 12 hr |
8 |
|||
| Group 2 |
0.1 μM lapatinib |
2 hr |
4 |
||
| 1 μM lapatinib |
2 hr |
4 |
|||
| 0.1% DMSO |
0 hr & 2 hr & 6 hr & 12 hr & 24 hr |
20 |
|||
|
Total |
|
|
44 |
||
| 5 |
SKBR3 |
Group 1 |
1 μM lapatinib |
12 hr |
4 |
| 0.1 μM lapatinib |
12 hr |
4 |
|||
| Group 2 |
0.1 μM lapatinib |
2 hr & 6 hr & 24 hr |
12 |
||
| |
1 μM lapatinib |
2 hr & 6 hr |
8 |
||
| |
0.1% DMSO |
0 hr & 2 hr & 6 hr & 12 hr & 24 hr |
20 |
||
|
Total |
|
|
48 |
||
| 6 |
SKBR3 |
Group 1 |
1 μM lapatinib |
12 hr |
4 |
| |
|
0.1 μM lapatinib |
12 hr |
4 |
|
| |
|
Group 2 |
0.1 μM lapatinib |
2 hr & 6 hr |
8 |
| |
|
|
1 μM lapatinib |
2 hr & 6 hr |
8 |
| |
|
|
0.1% DMSO |
0 hr & 2 hr & 6 hr & 12 hr & 24 hr |
20 |
| Total | 44 |