Table 1.

Summary of the major anticipated analyses of data from HAE-BOIS-Europe

Data source	Analyses
Survey data	Descriptive analyses, eg. · Treatments used · Medical resource utilization · Impact on work and school productivity · Reliance on volunteer and paid helpers · HADS scores and other HRQoL estimates
	Potential categorizations of HAE severity (frequency, pain, duration, etc)
	Estimated health utility weights for: · An acute HAE attack – based on survey responses mapped to the EQ-5D · Chronic disease – based on HADS scores mapped to the EQ-5D
Interviews	Key concepts important to patients with HAE · Providing context to survey-derived quantitative findings · Providing input into the draft conceptual model of HAE burden of illness