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Detection of IFN-γ in the liver 3 days p.i. in mice infected with 400 sporozoites. The KO mouse groups showed significantly higher concentrations of IFN-γ than the wild-type BALB/c mice, while the NK cell-depleted KO groups demonstrated a significant reduction in IFN-γ in the liver. Uninfected mice of all groups had only a low concentration of IFN-γ in the liver. The data are representative of two independent experiments.
