TABLE 1.
Number of lymphocytes in the liver
| Cell type | Mouse straina | Mean ± SD no. of cells (104)b
|
|
|---|---|---|---|
| Uninfected mice | 2 days p.i. | ||
| CD4 | BALB/c | 42.7 ± 6.5 | 44.9 ± 11.4 |
| IL-4−/− | 46.2 ± 17.8 | 42.7 ± 8.6 | |
| IL-4rα−/− | 45.2 ± 11.7 | 41.7 ± 4.4 | |
| CD8 | BALB/c | 4.7 ± 0.9 | 6.5 ± 1.9 |
| IL-4−/− | 5.1 ± 2.8 | 4.4 ± 1.9 | |
| IL-4rα−/− | 4.9 ± 2.5 | 4.6 ± 0.8 | |
| NK cells (CD3− DX5+) | BALB/c | 4.2 ± 1.7 | 5.8 ± 1.6 |
| IL-4−/− | 5.3 ± 1.7 | 9.5 ± 3.1* | |
| IL-4rα−/− | 5.1 ± 1.4 | 8.4 ± 0.3* | |
| NK T cells (CD3+/DX5+) | BALB/c | 24.8 ± 9.4 | 22.1 ± 7.1 |
| IL-4−/− | 25 ± 8.5 | 15.4 ± 4.1 | |
| IL-4rα−/− | 26.6 ± 14.3 | 17.7 ± 2.7 | |
| B cells | BALB/c | 13.9 ± 5.1 | 12.5 ± 5.2 |
| IL-4−/− | 15.8 ± 11.7 | 12.4 ± 6.6 | |
| IL-4rα−/− | 16.9 ± 13.4 | 10.2 ± 3.3 | |
a
Each group contains four animals.
b
*, significantly different from the uninfected mice strains and infected BALB/c mice (P < 0.05, Mann-Whitney U test).