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. 2012 Sep 11;7(9):e45100. doi: 10.1371/journal.pone.0045100

Figure 7. Gene expression in and around the sinuatrial ridges in Wt1- and Tbx18-mutant hearts.

Figure 7

(A–D) In situ hybridization analysis of Wt1 (A), Aldh1a2 (B), Tbx18 (C) and Gata4 (D) on sagittal sections trough the venous pole region of control, Wt1- and Tbx18-deficient hearts at E11.5 and E12.5. Genotypes and stages are as indicated. Green arrowheads point to the mesenchymal ridges that are important for the closure of the PPCs in control embryos; black arrows mark the remaining PPCs. icv, inferior cardinal vein; lu, lung; ra, right atrium.