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. 2012 Sep 11;7(9):e44317. doi: 10.1371/journal.pone.0044317

Figure 7. Known and proposed epitopes on RTB recognized by neutralizing and non-neutralizing RTB-specific mAbs.

Figure 7

Alignment of the B chain sequences from ricin (PDB 2AAI) and RCA-I (PDB 1RZO) using BLAST (www.ncbi.nlm.nih.gov). Boxed areas indicate regions of differences between RTB and RCB. Bolded text (highlighted by underlying brackets) delineates identified epitopes recognized by RTB-specific mAbs. The name of the corresponding mAb that binds the indicated epitope is written below the brackets. Regions 1-4, as indicated by vertical arrows, reflect regions of difference between RTB and RCB where mAb binding sites have yet to be ascribed.