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. 2012 Sep 11;7(9):e44317. doi: 10.1371/journal.pone.0044317

Table 1. Properties of RTB-specific mAbs produced in this study.

mAb Isotype SubD. Epitope KD [M] Vero cells-IC50 µg/ml (nM) THP-1 cells- apoptosis Passive protection
24B11a IgG1 38–43 4.2×10−9 0.60 (4) + +
SylH3b IgG1 n.d. n.d 3.38×10−9 0.75 (5) + +
JB4 IgG1 n.d. n.d. 2.01×10−10 0.80 (5.3) + +
B/J F9 IgG1 n.d. n.d 6.42×10−10 0.04 (0.27)
C/M A2 IgG1 194–198 2.2×10−9 5 (33)
TFTB-1a IgG1 169–184 5.63×10−9
a

, as reported by McGuinness and Mantis [25];

b

, as reported by Yermakova and Mantis [32].