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A. CD spectra of WT utrophin N-ABD and its mutants refolded from their denatured states at 8 M urea. B. Thermal melts of WT and mutants measured by CD at 222 nm recorded as a function of increasing temperature. Top panels of A and B show the overlapping data of freshly purified WT and refolded WT from its denatured state at 8 M urea.
