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. 2012 Oct;70(10):2287–2294. doi: 10.1016/j.apradiso.2012.07.010

Table 1.

Optimum reaction conditions and outcome for large scale preparation of [11C]SNAP-7941 (n=15).

Reaction temperature (°C) ≤25
Reaction time (min) 2
Amount of precursor (mg/mL) 2
Yield (GBq)a 2.9±1.6
Yield (%)b 17.5±3.6
Specific activity (GBq/μmoL)a 28.9±9.4
Radiochemical purity (%) >99
a

At end of synthesis (EOS).

b

Based on [11C]CH3OTf, corrected for decay.