Table 1.
Optimum reaction conditions and outcome for large scale preparation of [11C]SNAP-7941 (n=15).
Reaction temperature (°C) | ≤25 |
---|---|
Reaction time (min) | 2 |
Amount of precursor (mg/mL) | 2 |
Yield (GBq)a | 2.9±1.6 |
Yield (%)b | 17.5±3.6 |
Specific activity (GBq/μmoL)a | 28.9±9.4 |
Radiochemical purity (%) | >99 |
At end of synthesis (EOS).
Based on [11C]CH3OTf, corrected for decay.