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Influence of streptozotocin and ALDH2 on expression and activity of ALDH2, apoptosis and mitochondrial function. (A) ALDH2 expression; (B) ALDH2 enzymatic activity measured using spectrophotometry; (C) caspase-3 activity; (D) mitochondrial aconitase activity. Inset: Representative gel blots of ALDH2 and GAPDH (loading control) using specific antibodies. Mean ± SEM, n = 5 to 7 per group. *P < 0.05 versus FVB group; #P <0.05 versus FVB-STZ group.
