1 |
112315 |
Transmission across Chemical Synapses |
190 |
0 |
27 |
17.26 |
0.2117 |
2 |
112316 |
Neuronal System |
283 |
0 |
32 |
13.74 |
0.2232 |
3 |
hsa04723 |
Retrograde endocannabinoid signaling |
116 |
4.68E-14 |
18 |
18.85 |
0.1713 |
4 |
112314 |
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell |
136 |
4.48E-13 |
18 |
16.08 |
0.1599 |
5 |
hsa04727 |
GABAergic synapse |
98 |
5.48E-13 |
16 |
19.84 |
0.165 |
6 |
hsa04080 |
Neuroactive ligand-receptor interaction |
401 |
4.42E-12 |
26 |
7.88 |
0.1678 |
7 |
977441 |
GABA A receptor activation |
12 |
7.38E-09 |
7 |
70.87 |
0.3281 |
8 |
975298 |
Ligand-gated ion channel transport |
25 |
1.41E-08 |
8 |
38.88 |
0.2017 |
9 |
977443 |
GABA receptor activation |
53 |
1.30E-07 |
9 |
20.63 |
0.1318 |
10 |
hsa04724 |
Glutamatergic synapse |
134 |
2.62E-07 |
12 |
10.88 |
0.1073 |
11 |
983712 |
Ion channel transport |
61 |
3.20E-07 |
9 |
17.92 |
0.1206 |
12 |
420499 |
Class C/3 (Metabotropic glutamate/pheromone receptors) |
15 |
5.19E-07 |
6 |
48.6 |
0.2313 |
13 |
888590 |
GABA synthesis, release, reuptake and degradation |
19 |
1.52E-06 |
6 |
38.37 |
0.1891 |
14 |
399719 |
Trafficking of AMPA receptors |
30 |
1.33E-05 |
6 |
24.3 |
0.1313 |
15 |
399721 |
Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity |
30 |
1.33E-05 |
6 |
24.3 |
0.1313 |
16 |
112310 |
Neurotransmitter Release Cycle |
36 |
3.03E-05 |
6 |
20.25 |
0.1146 |
|
Rank |
DiseaseID |
DiseaseName |
N |
Pvalue |
AE |
RE |
MJI |
|
1 |
MESH:D001764 |
Blepharospasm |
699 |
0 |
45 |
5.52 |
0.1398 |
2 |
MESH:D012563 |
Schizophrenia, Paranoid |
649 |
3.18E-12 |
40 |
5.29 |
0.1265 |
3 |
MESH:D002385 |
Cataplexy |
723 |
1.33E-11 |
41 |
4.86 |
0.1264 |
4 |
MESH:D020187 |
REM Sleep Behavior Disorder |
506 |
1.44E-11 |
34 |
5.76 |
0.1149 |
5 |
MESH:D020821 |
Dystonic Disorders |
837 |
4.52E-10 |
41 |
4.2 |
0.1226 |
6 |
MESH:D015877 |
Miosis |
1000 |
1.94E-09 |
44 |
3.77 |
0.1273 |
7 |
MESH:D001925 |
Brain Damage, Chronic |
1732 |
1.20E-08 |
59 |
2.92 |
0.1582 |
8 |
MESH:D000341 |
Affective Disorders, Psychotic |
700 |
1.50E-08 |
34 |
4.17 |
0.1056 |
9 |
MESH:D007415 |
Intestinal Obstruction |
1293 |
2.33E-08 |
48 |
3.18 |
0.1334 |
10 |
MESH:D011681 |
Pupil Disorders |
1612 |
2.61E-08 |
55 |
2.93 |
0.1486 |
|
Rank |
DrugID |
DrugName |
N |
Pvalue |
AE |
RE |
MJI |
|
1 |
DB01595 |
Nitrazepam |
20 |
2.92E-08 |
10 |
29.64 |
0.3294 |
2 |
DB00349 |
Clobazam |
19 |
4.26E-08 |
9 |
28.08 |
0.3083 |
3 |
DB00475 |
Chlordiazepoxide |
19 |
4.26E-08 |
9 |
28.08 |
0.3083 |
4 |
DB00683 |
Midazolam |
19 |
4.26E-08 |
9 |
28.08 |
0.3083 |
5 |
DB00690 |
Flurazepam |
19 |
4.26E-08 |
9 |
28.08 |
0.3083 |
6 |
DB00842 |
Oxazepam |
19 |
4.26E-08 |
9 |
28.08 |
0.3083 |
7 |
DB01558 |
Bromazepam |
19 |
4.26E-08 |
9 |
28.08 |
0.3083 |
|
Rank |
OrganID |
OrganName |
N |
Pvalue |
AE |
RE |
MJI |
|
1 |
brain |
brain |
363 |
0 |
260 |
15.42 |
0.8581 |