Table 5.

Identification of Previously Undiscovered Components by IPAD

PathwayID	PathwayName	p-value	AE	RE	MJI	C
1430728	Metabolism	4.32E-35	525	2.19	0.34	93
556833	Metabolism of lipids and lipoproteins	1.00E-13	175	2.25	0.27	91
453279	Mitotic G1-G1/S phases	2.41E-42	47	27.44	0.33	87
200137	AP-1 transcription factor network	2.36E-06	44	2.97	0.32	87
453279	Mitotic G1-G1/S phases	2.77E-09	78	2.73	0.30	87
200120	Direct p53 effectors	6.09E-07	70	2.4	0.27	85
69278	Cell Cycle, Mitotic	1.81E-14	166	2.37	0.28	82
1640170	Cell Cycle	1.51E-12	183	2.11	0.26	80
535734	Fatty acid, triacylglycerol, and ketone body metabolism	1.38E-07	81	2.35	0.26	79
71291	Metabolism of amino acids and derivatives	7.54E-15	120	2.9	0.33	76
DiseaseID	DiseaseName	p-value	AE	RE	MJI	C
MESH:D015228	Hypertriglyceridemia	1.60E-192	4573	2.09	0.77	79
MESH:D009468	Neuromuscular Diseases	4.34E-07	117	2.04	0.41	74
MESH:D009468	Neuromuscular Diseases	2.16E-293	4573	2.52	0.82	74
MESH:D052016	Mucositis	4.99E-199	4572	2.11	0.77	72
MESH:D002543	Cerebral Hemorrhage	7.21E-128	4572	1.8	0.73	72
MESH:D006463	Hemolytic-Uremic Syndrome	3.65E-215	4570	2.18	0.78	72
MESH:D020246	Venous Thrombosis	6.59E-106	4573	1.71	0.72	70
MESH:D013923	Thromboembolism	1.78E-123	4573	1.79	0.73	70
DrugID	DrugName	p-value	AE	RE	MJI	C
PA449383	Docetaxel	3.08E-02	52	1.89	0.36	24
PA449780	Glutathione	1.74E-10	20	10.48	0.24	13
PA131301952	Gefitinib	8.52E-17	29.88	10.84	0.395	8
PA451283	Rosiglitazone	7.73E-22	41.4	10.58	0.386	5
PA448803	Carboplatin	2.57E-15	27	11.36	0.397	5
OrganID	OrganName	p-value	AE	RE	MJI	C
liver	Liver	1.82E-17	179	2.72	0.40	84