Table 1.
Characteristics of the simulated datasets.
| LD thr.: r 2 ≥ .0.60 | LD thr.: r2 ≥ 0.80 | ||||||
|---|---|---|---|---|---|---|---|
| sim | GRR | B | SNPs/B | r 2 | B | SNPs/B | r 2 |
| 1 | 1.5/3.0 | 43 | 5.0 [6.50] | 0.94 [0.13] | 63 | 3 [5.50] | 0.97 [0.06] |
| 2 | 1.5/3.0 | 36 | 6.5 [11.50] | 0.95 [0.08] | 55 | 4 [6.00] | 0.98 [0.05] |
| 3 | 1.5/3.0 | 58 | 3.5 [5.00] | 0.97 [0.07] | 76 | 3 [3.00] | 0.98 [0.06] |
| 4 | 2.0/4.0 | 24 | 8.5 [29.50] | 0.97 [0.07] | 67 | 4 [4.00] | 0.98 [0.06] |
| 5 | 2.0/4.0 | 34 | 4.5 [14.00] | 0.95 [0.17] | 61 | 3 [6.00] | 0.98 [0.09] |
| 6 | 2.0/4.0 | 39 | 5.0 [6.50] | 0.97 [0.19] | 70 | 4 [3.75] | 0.99 [0.05] |
| 7 | 3.0/6.0 | 22 | 9.0 [28.25] | 0.96 [0.07] | 49 | 5 [6.00] | 0.98 [0.07] |
| 8 | 3.0/6.0 | 45 | 5.0 [10.00] | 0.98 [0.10] | 80 | 3 [3.00] | 0.98 [0.06] |
| 9 | 3.0/6.0 | 34 | 8.5 [14.50] | 0.93 [0.11] | 72 | 3 [4.00] | 0.96 [0.09] |
GRR, heterozygote/homozygote Genotype Relative Risk (GRR); B, number of blocks; SNPs/B, median number [Interquartile Range (IQR)] of SNPs within each block; r2, median [Interquartile Range (IQR)] pairwise r2 within each block. The described parameters are reported for blocks defined using thresholds of LD corresponding to r2 ≥ 0.6 and 0.8 respectively.