Table 1.

Quantification of polarity of dendritic and axonal proteins

Transfected	Dendrite:Axon Polarity Index
TfR-GFP WT	9.1 ± 3.0 (25)
TfR-GFP Y20A	1.3 ± 0.2 (25)#
TfR-GFP F23A	1.4 ± 0.2 (25)#
TfR-GFP WT+ p CD M 8	9.6 ± 3.8 (30)
TfR-GFP WT + pCMD8-Hub	1.6 ± 0.5 (30)*
m Cherry-Tubulin	1.2 ± 0.2 (30)
GFP	1.2 ± 0.2 (25)
Transfected	µlA-WT	µlA-W408S
TfR-GFP WT	8.1 ± 2.6 (30)	1.3 ± 0.3 (30)*
mGluR1-GFP	9.0 ± 2.7 (35)	1.6 ± 0.4 (35)*
NR2A-GFP	6.3 ± 2.2 (30)	1.4 ± 0.4 (30)*
NR2B-GFP	9.6 ± 2.6 (27)	1.3 ± 0.3 (33)*
GluR1-GFP	8.1 ± 2.0 (25)	7.8 ± 2.0 (30)
SEP-GluR2	7.0 ± 1.4 (30)	6.9 ± 2.8 (28)
NgCAM	0.1 ± 0.1 (30)	0.1 ± 0.1 (30)
Endogenous	µlA-WT	µlA-W408S
NR2A	11.8 ± t 2.7 (30)	1.3 ± 0.2 (40)*
NR2B	8.9 ± 2.1 (30)	1.1 ± 0.3 (35)*
GluR1	7.7 ± 1.3 (30)	6.9 ± 2.2 (30)
GluR2	6.6 ± 1.5 (30)	6.2 ± 1.8 (30)
MAP2	14.4 ± t 2.6 (30)	13.7 ± 2.4 (30)

Values are expressed as mean ± SD (n)

(n) Number of cells analyzed.

^#Significantly different from TfR-GFP WT (p<0 .01)

^*Significantly different from control group (p<0.01)

Polarity index was calculated as described in Experimental Procedures