TABLE 1.
Total genital tract immunoglobulin levels from uninfected and infected volunteers
| Sample type and antibody class | Median Ig levels (μg/ml) (range [n])
|
|
|---|---|---|
| No previous history | Current Infection | |
| Cervical mucus | ||
| IgG | 15.6 (0.1-178.6 [14]) | 6.1 (0.3-89.8 [11]) |
| IgM | 0.3 (0.0-64.0 [14]) | 4.6 (0.1-34.5 [11]) |
| IgA | 9.6 (0.2-121.5 [14]) | 8 (0.0-88.5 [11]) |
| Seminal plasma | ||
| IgG | 75.7 (49.5-187.0 [4]) | 75.5 (34.6-727.5 [9]) |
| IgM | 1.2 (0.4-7.5 [4]) | 3.5 (1.1-47.0 [9]) |
| IgA | 79.3 (54.4-80.1 [4]) | 42.5a (27.0-348.7 [9]) |
a
P < 0.05 compared with results for uninfected controls (as determined by the Kolmogorov-Smirnov test).