TABLE 1.

Comparison of the kinetics for deposition of C3 onto cells of prototypic serotype A and serotype B strains via the classical and alternative pathways^a

Kinetics parameter	Value for classical pathwayb for:		P (A vs B)	Value for alternative pathwayc for:		P (A vs B)
	Serotype A 36801	Serotype B 36803		Serotype A 36801	Serotype B 36803
k′d	0.18 ± 0.04	0.22 ± 0.05	0.011	0.05 ± 0.007	0.15 ± 0.03	0.011
t0e	−0.61 ± 0.69	0.65 ± 0.31	0.015	6.1 ± 1.0	6.2 ± 0.57	0.88

^aResults shown are the means ± standard deviations of results from four independent experiments. Analysis of each pair was done by Student's t test.

^bC3 deposition via the classical pathway was determined by incubation of C. albicans yeast cells in 40% untreated PHS.

^cC3 deposition via the alternative pathway was determined by incubation of C. albicans yeast cells in 40% PHS that had been treated with Mg-EGTA.

^dk′, pseudo first-order rate constant determined as described in the legend to Fig. 4.

^et₀, x intercept of a pseudo first-order rate plot. t₀ is an estimate of the lag or induction period, in minutes, before the linear portion of the pseudo first-order rate plot begins (Fig. 4).