Figure 3.

Across many cell types, more conserved islands overlap RFBSs than ncRNAs. (A) Number of novel ncRNAs, ucRFBSs, and insulators discovered with each additional tissue or cell type investigated. The number of conserved islands assigned to each category initially increases as a power-law. (B) Extrapolation to additional cell types of the number of unannotated conserved islands explained by ncRNAs, unannotated RFBSs and insulators (based on the slopes in the left panel). Assuming that there are a total of 100, 200, 500, 1000 or 1500 distinct cell-types or conditions, we calculated the total number of conserved islands that would overlap ncRNAs, insulators or other RFBSs.