Table 2.
Preliminary identification of candidate proteins significantly associated with RV EF changes pre-race, at the finish line and post-race.
| m/z ratio | Pattern | Change | P value | Name | Protein ID |
|---|---|---|---|---|---|
| Pre-race protein analysis | |||||
| 17772.3 | 2 | 1.79 | 0.0426 | None | |
| 17897.5 | 2 | 3.38 | 0.0074 | IL1RN |
Interleukin-1 receptor agonist protein |
| Protein CX | Endothelial-overexpressed lipopolysaccharide-associated factor 1 | ||||
| 18036.4 | 2 | 2.16 | 0.0168 | IL1A | Interleukin-1 alpha (precursor) |
| IL8 |
Interleukin-8 (precursor) |
||||
| 8922.3 | 2 | 0.70 | 0.0089 | CCL8 | C-C motif chemokines 8 |
| 16865.8 | 3 | 2.16 | 0.0230 | none | |
|
| |||||
| Finish line protein analysis | |||||
| 10806.6 | 1 | 1.86 | 0.0004 | S100A8 | Calgranulin-A |
| 10837.1 | 1 | 1.78 | 0.0047 | S100A8 | Calgranulin-A |
| 13285.2 | 1 | 1.95 | 0.0015 | IL13 SELH |
Interleukin-13 (precursor) Selenoprotein H |
| 13252.4 | 1 | 2.17 | 0.0015 | None | |
| 22283.7 | 1 | 0.82 | 0.0241 | None | |
| 22203.0 | 1 | 0.80 | 0.0155 | CLCF1 | Cardiotrophin-like cytokine factor 1 |
| 3375.45 | 1 | 0.73 | 0.0085 | DEF3 | Neutrophil defensin 3 |
| 10753.8 | 1 | 1.91 | 0.0053 | CCKN | Cholecystokinin |
| 16706.3 | 5 | 0.53 | 0.0003 | CALM1 IL1F10 |
Calmodulin Interleukin-1 family member 10 |
| 12671.7 | 1 | 2.01 | 0.0055 | SPEG | Striated muscle preferentially expressed protein kinase |
| 10899.6 | 1 | 1.81 | 0.0101 | None | |
| 32038.5 | 1 | 0.78 | 0.0144 | FCN1 | Ficolin-1 |
| 116572 | 2 | 0.58 | 0.0149 | CORIN | Atrial natriuretic peptide-converting enzyme |
| LIPE | Hormone-sensitive lipase | ||||
| 10418.6 | 1 | 2.00 | 0.0006 | CRP | C-reactive protein (precursor) |
| S100A1 | Protein S100-A1 | ||||
| CASP1 | Caspase-1 (precursor) | ||||
| SUMO4 | Small ubiquitin-related modifier 4 | ||||
| 185233 | 3 | 0.34 | 0.0423 | None | |
| 10970.5 | 1 | 1.73 | 0.0201 | DEFA6 | Defensin-6 (precursor) |
|
| |||||
| Post-race protein analysis | |||||
| 11654.2 | 4 | 1.38 | 0.0224 | FKBP1B | Peptidyl-prolyl-cis-transisomerase FKBP1B (precursor) |
| SAA1 | Serum amyloid A protein (precursor) | ||||
| GPHA2 | Glycoprotein hormone alpha-2 (precursor) | ||||
| 11603.7 | 4 | 1.35 | 0.0378 | SAA1 | Serum amyloid A protein (precursor) |
| 11629.3 | 4 | 1.40 | 0.0224 | SAA1 | Serum amyloid A protein (precursor) |
| 11699.7 | 4 | 1.39 | 0.0052 | SAA1 | Serum amyloid A protein (precursor)) |
| 11699.7 | 4 | 1.39 | 0.0052 | KCNE3 | Potassium voltage-gated channel subfamily E member 3 |
| 11885.4 | 4 | 1.59 | 0.0083 | NPPB | Natriuretic peptide B (precursor |
| 11320.9 | 4 | 1.59 | 0.0454 | IL8 | Interleukin-8 (precursor) |
| 17772.3 | 2 | 0.67 | 0.0232 | None | |
| 17453.6 | 2 | 0.72 | 0.0126 | IL18P | Interleukin-18-binding precursor (precursor) |
| 17578.4 | 2 | 0.67 | 0.0092 | TREM1 | Triggering receptor expressed on myeloid cells 1 |
| IL26 | Interleukin-26 (precursor) | ||||
| 17375.4 | 2 | 0.71 | 0.0194 | IL1B | Interleukin-1-beta |
| IL7 | Interleukin-7 (precursor) | ||||
| 9709.5 | 2 | 1.32 | 0.0335 | CHGA | Chromogranin A (precursor) |
| 17381.1 | 2 | 0.70 | 0.0207 | IL1B IL7 |
Interleukin-1 beta (precursor) Interleukin-7 (precursor) |
| 10418.6 | 1 | 1.57 | 0.0426 | CRP | C-reactive protein |
| S100A1 | Protein s100-A1active | ||||
| CASP1 | Caspase-1 (precursor) | ||||
| SUMO4 | Small ubiquitin-related modifier 4 (precursor) | ||||
| 11207.8 | 4 | 2.09 | 0.0452 | SAA1 | Serum amyloid A protein (precursor) |
| 11052.8 | 3 | 1.45 | 0.0424 | None | |