TABLE 3.
Role of NeuAc in the persistence of NTHi 2019 in the gerbil middle eara
| Strain | Inoculum (log10 no. of CFU) | Log10 no. of CFUb recovered on:
|
|
|---|---|---|---|
| Day 1 | Day 3 | ||
| NTHi 2019 | 7.4 | 7.0 ± 0.29 | 6.9 ± 0.21 |
| NTHi 2019 siaB | 7.5 | 1.2 ± 0.22 | 0.17 ± 0.17 |
a
Groups of Mongolian gerbils were infected with NTHi 2019 and an isogenic siaB mutant by injection through the tympanic membrane (described in Materials and Methods), and bacterial counts for middle ear lavage fluid were determined at days 1 and 3 postinfection. The limit of detection was 10 CFU.
b
Mean ± standard error of the mean for 10 animals.