Table 3.
Treatment | Body weight (gm) | Liver weight (gm) | Liver index (LW/BW %) |
---|---|---|---|
Group 1 (normal rats) | 347 ± 5.04 | 9.70 ± 0.16 | 2.79 ± 0.21 |
Group 2 (rats with cirrhosis) | 183 ± 2.32 | 9.44 ± 0.60 | 5.18 ± 0.06** |
Group 3 (silymarin-treated rats) | 347 ± 3.58 | 10.28 ± 0.66 | 2.97 ± 0.35* |
Group 4 (treatment with the BR extract at 250 mg/kg dose) | 255 ± 2.91 | 10.03 ± 0.46 | 3.93 ± 0.44* |
Group 5 (treatment with the BR extract at 500 mg/kg dose) | 376 ± 5.67 | 9.71 ± 0.71 | 2.59 ± 0.36* |
Data were expressed as Mean ± SEM. Means between the silymarin-treated Group 3, low-dose BR-treated Group 4, and high-dose BR-treated Group 5 had significant differences when compared with the cirrhosis control Group 2 with *P < 0.001 and compared with the normal control Group 1 with **P < 0.001.