TABLE 1.

Effects of anti-IL-18 IgG or rIL-18 administration on blood counts in GBS-infected neonatal mice^a

Treatment	Blood colony counts (mean ± SD log CFU/ml) at h:
	48	72
PBS	4.56 ± 1.27	5.9 ± 1.19
Anti-IL-18 IgG	7.16 ± 1.34b	7.40 ± 1.56b
rIL-18	2.31 ± 1.08b	4.01 ± 0.96b

^aNeonatal mice were treated with 0.5 μg of goat polyclonal anti-IL-18 IgG or 200 ng of rIL-18 at 6 h before challenge with GBS (60 CFU/pup). Data represent three observations each conducted on a different animal.

^bThe P value in a comparison with the respective PBS control was <0.05, as determined by analysis of variance and the Student-Newman-Keuls test.