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. 2012 Apr 23;23(9):992–1002. doi: 10.1089/hum.2011.159

FIG. 3.

FIG. 3.

Comparison of the antitumor activity of ZD55-TRAIL and ZD55-TRAIL-IETD. (A) Huh-7, SW620, HeLa, and NCI-H460 cells were infected with ZD55-TRAIL or ZD55-TRAIL-IETD at MOIs of 0.1, 1, 5, and 10. After 96 hr, cell survival was determined by MTT assay. Results are expressed as a percentage relative to untreated controls and data represent the mean±SD of three independent experiments. (B) Lysates of NCI-H460 cells infected with the recombinant adenoviruses were prepared to analyze the expression of TRAIL and E1A proteins. Mock-infected cells were included as a control. β-Actin was used as a protein loading control. The result shown is representative of three separate experiments.