Table 1.
Baseline Demographic Characteristics of Patients with Type 2 Diabetes Mellitus and Healthy Subjectsa
| Patients with T2DM | ||||
|---|---|---|---|---|
| GLA + MET (n = 14) | SU + MET (n = 17) | DPP-4-I + MET (n = 17) | Healthy subjects (n = 17) | |
| Male n (%) | 11 (78.6) | 11 (64.7) | 10 (58.8) | 9 (52.9) |
| Age (years) | 65.5 (6.5) | 64.9 (6.5) | 62.6 (8.4) | 64.9 (6.3) |
| Weight (kg) | 88.5 (10.6) | 90.6 (14.9) | 86.4 (12.7) | 80.7 (16.0) |
| Height (cm) | 170.9 (7.1) | 168.8 (10.8) | 169.1 (7.2) | 172.5 (10.4) |
| Body mass index (kg/m2) | 30.3 (2.7) | 31.6 (2.7) | 30.1 (3.2) | 26.9 (3.7) |
| HbA1c (%) | 7.1 (0.3) | 7.0 (0.5) | 6.6 (0.4) | 5.6 (0.3) |
| Duration of diabetes (years) | 8.9 (3.3) | 7.9 (4.2) | 6.9 (3.9) | NA |
| Fasting glucose (mmol/liter) | 7.3 (1.6)b | 7.5 (1.0)b | 7.6 (1.7)b | 5.5 (0.5) |
| Fasting insulin (pmol/liter) | 14.9 (7.8) | 27.5 (21.9)b | 15.3 (7.3)b | 9.2 (3.9) |
| Fasting proinsulin (pmol/liter) | 7.0 (3.4)b | 14.2 (8.3)b,c,d | 5.6 (3.2)b | 4.5 (1.9) |
a
Values are mean (standard deviation) unless otherwise stated. NA, not applicable.
b
p < .05 versus healthy subjects.
c
p < .05 versus GLA plus MET.
d
p < .05 versus DPP-4-I plus MET.