TABLE 1.
Antibodies against melanin inhibit the growth of F. pedrosoia
| Cell type | No. of CFU (mean ± SD) after antibody treatment
|
P | |
|---|---|---|---|
| Irrelevant IgG | Antibodies against melanin | ||
| Conidia | 388 ± 99 | 11 ± 8 | <0.0001 |
| Sclerotic cells | 184 ± 24 | 122 ± 14 | <0.005 |
a
Inhibition of fungal growth was determined after the treatment of F. pedrosoi with human antibodies against melanin or with irrelevant IgG, followed by plating onto SDA. After incubation of SDA plates for 15 days at 28°C, means and standard deviations were obtained by the estimation of the number of CFU for three different experiments. P, t test significance of differences between the results obtained after treatment with irrelevant IgG or anti-melanin antibodies.