Table 2.
Association [OR (95% CI)] between urinary phthalate metabolites and diabetes among women 20–79 years of age (NHANES 2001–2008).
Urinary phthalate metabolite | Model 1a | Model 2b | Model 3c | Model 4d | |||
---|---|---|---|---|---|---|---|
MEP | |||||||
Q1 | |||||||
Q2 | 1.04 (0.65–1.68) | 1.00 (0.63–1.59) | 0.95 (0.60–1.51) | 0.93 (0.58–1.49) | |||
Q3 | 1.08 (0.62–1.88) | 1.17 (0.64–2.13) | 1.09 (0.61–1.96) | 1.19 (0.65–2.20) | |||
Q4 | 1.10 (0.58–2.06) | 0.94 (0.49–1.80) | 0.89 (0.47–1.67) | 0.89 (0.48–1.68) | |||
MnBP | |||||||
Q1 | |||||||
Q2 | 1.37 (0.84–2.24) | 1.32 (0.80–2.18) | 1.29 (0.78–2.13) | 1.31 (0.78–2.22) | |||
Q3 | 2.01 (1.21–3.36) | 1.76 (1.05–2.94) | 1.71 (1.04–2.81) | 1.73 (1.01–2.96) | |||
Q4 | 1.32 (0.76–2.28) | 1.06 (0.59–1.89) | 1.06 (0.61–1.85) | 1.14 (0.63–2.04) | |||
MiBP | |||||||
Q1 | |||||||
Q2 | 1.04 (0.66–1.66) | 1.06 (0.67–1.68) | 1.04 (0.66–1.67) | 1.03 (0.64–1.67) | |||
Q3 | 1.47 (0.85–2.53) | 1.65 (0.91–2.98) | 1.69 (0.93–3.06) | 1.71 (0.92–3.16) | |||
Q4 | 1.85 (1.04–3.27) | 1.97 (0.99–3.93) | 1.95 (0.99–3.85) | 1.80 (0.89–3.65) | |||
MBzP | |||||||
Q1 | |||||||
Q2 | 0.81 (0.43–1.51) | 0.85 (0.45–1.60) | 0.78 (0.41–1.49) | 0.84 (0.44–1.60) | |||
Q3 | 1.73 (1.12–2.66) | 1.84 (1.18–2.88) | 1.80 (1.16–2.81) | 1.90 (1.18–3.08) | |||
Q4 | 1.60 (0.86–2.97) | 1.95 (1.09–3.48) | 1.96 (1.11–3.47) | 1.99 (1.14–3.49) | |||
MCPPe | |||||||
Q1 | |||||||
Q2 | 0.78 (0.46–1.33) | 0.85 (0.50–1.44) | 0.83 (0.49–1.43) | 0.76 (0.44–1.33) | |||
Q3 | 1.46 (0.95–2.25) | 1.54 (0.98–2.42) | 1.55 (0.98–2.44) | 1.47 (0.90–2.41) | |||
Q4 | 1.45 (0.84–2.49) | 1.62 (0.97–2.71) | 1.68 (1.03–2.75) | 1.64 (0.96–2.79) | |||
∑DEHP (MEHP, MEHHP, and MEOHP)f | |||||||
Q1 | |||||||
Q2 | 1.53 (0.92–2.54) | 1.58 (0.97–2.57) | 1.53 (0.95–2.48) | 1.47 (0.90–2.40) | |||
Q3 | 1.81 (1.10–2.99) | 1.85 (1.13–3.02) | 1.73 (1.03–2.91) | 1.70 (0.96–3.03) | |||
Q4 | 1.45 (0.84–2.51) | 1.66 (0.90–3.05) | 1.53 (0.82–2.87) | 1.43 (0.75–2.75) | |||
Q, quartile. For each of the metabolites, Q1 is the reference. aAdjusted for urine creatinine. bAdjusted for urine creatinine, age, race/ethnicity, education, poverty status, and fasting time. cAdjusted for urine creatinine, age, race/ethnicity, education, poverty status, fasting time, total caloric intake, total fat intake, smoking status, and physical activity. dAdjusted for urine creatinine, age, race/ethnicity, education, poverty status, fasting time, total caloric intake, total fat intake, smoking status, physical activity, BMI, and waist circumference. eSmoking and physical activity were not included in this analysis. fSmoking was not included in this analysis. |