FIG. 4.

Recovery of wild-type and mutant S. pyogenes following intraperitoneal challenge. Groups of six C57BL/6J mice were challenged intraperitoneally as described for Fig. 3. At the indicated time points, the numbers of CFU that could be recovered from the peritoneal cavity and the spleen were determined (top and bottom panels, respectively). Each symbol represents the number of CFU of the indicated strain recovered from an individual mouse, and the bar represents the mean value obtained for each group of six mice.