Figure 3. P. gingivalis suppressed AP-1 and NF-κB activity.

Jurkat T-cells (10⁶ cells/ml) were transfected with either AP-1 (A) or NF-κB (B) luciferase reporter plasmids. The cells were treated with viable or heat-killed P. gingivalis (10⁸ CFU/ml, MOI:100) for 24 h. AP-1 and NF-κB activation were determined by measuring luciferase activity, which was normalized against the internal control Renilla. *-p<0.05; **-p<0.01 (Student's t-test).