Table 2. Liver-specific transcription factors and liver-enriched genes that are potentially targeted by altered microRNAs as predicted by TargetScan 6.0.

microRNAs	liver-specific transcription factor	liver-enriched gene
has-miR-3646	CRTC2; FOXA1; HNF4A(HNF4); NF1; POU2F1;	APOB; ACACA; PFKFB3;
	SP1;GATA4; NR5A2; STAT1;HNF4G	MET; HNF4A; NR5A2; APP
has-miR-3679-3p	CEBPA; CRTC2; CTF; CTF1; NF1; RELA;	ALDOB; PFKFB3; CEBPA;
	POU2F1; SP1;USF1; RXRA; NR5A2; STAT1	MET; NR5A2
has-miR-155	CEBPB; FOS; CRTC2; RELA; POU2F1; SP1;	LPL; CETP; R5A2
	RXRA;NR1H3; NR5A2; STAT1
has-miR-17	CRTC2; FOXA1; POU2F1; STAT3; GATA6;	PFKFB3; DLR; PP
	RXRG;HNF4G
has-miR-31	POU2F1; SP1; FOXM1; RXRB; NR5A2	PFKFB3;GYPB;MET; NR5A2; APP
has-miR-1973	FOXM1; GATA4	PFKFB3; LDLR
has-miR-762	JUN; CEBPA; NR2F1; CTF; HNF1A; HNF4A;	LPL; ACACA; hnf1; PKLR; LDLR;
	NFKB2;RELA; POU2F1; SP1;USF2; RXRB;	CEBPA; MET; HNF4A; srebp2
	RXRA; STAT3;SREBF1(SREBF-1c); SREBF2;
	GATA4; GATA6; NR1H2
has-miR-671-5p	CEBPA; HNF1A(HNF1); HNF4A; NFKB1;	ACACA; hnf1; LDLR; CEBPA; HNF4A
	POU2F1; SP1;FOXM1; RXRA; STAT3; SREBF1
has-miR-542-5p	NF1; STAT1	PKLR; MET
has-miR-1185	CRTC2; POU2F1; USF2; FOXM1; NR5A2	LPL; LDLR; NR5A2; SAA2
has-miR-539	CRTC2; FOXA1; NFKB1(NFKB); POU2F1; SP1;	LDLR; HNF4A; srebp2
	RXRB;RXRA; STAT3; SREBF2; GATA4; GATA6;
	Onecut1A;HNF4G
has-miR-542-3p	JUN(CJUN); CRTC2; HNF1A; HNF4A; RXRB;	hnf1; LDLR; MET; HNF4A; srebp2;
	RXRA;SREBF2; GATA4; NR5A2	NR5A2
has-miR-1290	FOXA1; NF1; POU2F1; SP1; GATA4	FOXA2; MET
has-miR-136	CRTC2; HNF1A; NF1; POU2F1; SP1; HNF1B;	apob; PL; hnf1; PKLR; CETP; NOS2;
	GATA6;NR5A2	NR5A2; SAA2
has-miR-424	CTF; HNF1A; HNF4A; NFKB1; NF1; POU2F1;	APOC3; ACACA; ALDOB; hnf1; NOS2;
	GATA4	HNF4A; APP
has-miR-1246	NF1; SP1; RXRA; NR5A2; Onecut1A; FOXM1B	FOXM1B; NR5A2; SAA2